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Syncope-Asystole Latency Time in Tilt Table Test: The SALT-TILT Study

RECRUITINGSponsored by Azienda Ospedaliera di Bolzano
Actively Recruiting
SponsorAzienda Ospedaliera di Bolzano
Started2024-03-20
Est. completion2026-03
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

Syncope is a common presenting condition. Pacemaker implantation can significantly reduce syncope recurrences in reflex syncope. However, despite careful selection, a substantial proportion of patients treated with pacemakers suffer recurrences of syncope. It is thought that a pronounced vasodepressor component may hinder the efficacy of pacing in patients, preventing adequate cerebral perfusion during the reflex, thus relativizing the anti-bradycardia function of the pacemaker to prevent syncope. It is hypothesised that the time elapsed from the actual loss of consciousness to the asystole recorded on the ECG during Tilt Table Test may be predictive in terms of response to pacemaker therapy, so this parameter becomes the subject of the present study.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Patients eligible for invasive treatment according to the ESC Guidelines for pacing 2021
* Written informed consent

Exclusion Criteria:

* Other condition which explains syncope cause other than reflex syncope
* Structural heart disease (valvular, ischaemic, cardiomyopathies)
* Pregnancy
* Patient denial to be recorded on video during tilt table test

Conditions5

AsystoleHeart DiseaseNeurally Mediated SyncopePacemakerSyncope

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