|

Improving the Success Rate for Thoracic Radiotherapy Through Specific Cardiac Substructure Dosimetry: Location Matters. (LOCATION MATTERS)

RECRUITINGSponsored by Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Actively Recruiting
SponsorFondazione IRCCS Istituto Nazionale dei Tumori, Milano
Started2024-03-29
Est. completion2029-03-29
Eligibility
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06361784

Summary

The prospective study LOCATION MATTERS aims to investigate the radiation-induced damage to the heart and the cardiovascular system in patients treated with thoracic radiotherapy. Patients enrolled in the study will complete a set of extensive measures at the baseline, end of RT, and 9 months after treatment. Ultrasound exams, CT scans, pulmonary tests and wearable devices will assess functional and morphological parameters and the association with their variation and the dose delivered to the heart substructures and to the normal lung.

Eligibility

Healthy volunteers accepted
Inclusion Criteria:

* Patients with NSCLC
* Patients with locally advanced disease (Stage 3)
* Patients treated with RT at Fondazione IRCCS Istituto Nazionale dei Tumori

Exclusion Criteria:

* Previous thoracic radiotherapy
* Previous heart surgery

Conditions2

Heart DiseaseLocally Advanced Lung Non-Small Cell Carcinoma

Browse More Trials

Heart Disease trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.