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A Study on Relationship Between Resected Normal Liver Parenchymal Volume（RNLV）and Post-Hepatectomy Liver Failure (PHLF)

RECRUITINGSponsored by National Natural Science Foundation of China
Actively Recruiting
SponsorNational Natural Science Foundation of China
Started2022-12-01
Est. completion2026-12-31
Eligibility
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06366048

Summary

The post-hepatotectomy liver failure (PHLF) is still the most worrisome complication of hepatic resection. Surgeons have always been making efforts to preoperatively predict PHLF using kinds of techniques, scoring systems, and variables. The investigators of this study tried to create an individual predictive model based on the variable, resected normal parenchymal volume (RNLV), then assessing the performance and value of the model in clinical practice.

Eligibility

Healthy volunteers accepted
Inclusion criteria:

* selective hepatectomies;
* histologically confirmed as HCC and ICC
* complete and accessible data

Exclusion criteria:

* any history of Associated Liver Partition and Portal vein ligation for Staged hepatectomy (ALPPS)
* any history of portal vein embolism (PVE)
* any history of tumor rupture
* emergency surgery
* pathologically diagnosed with neither HCC nor ICC
* concomitant resection of gastrointestinal organs, spleenectomy or other organs

Conditions2

Liver DiseaseLiver Failure

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