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Prediction Models for Complications After CRT in Esophageal Cancer

RECRUITINGSponsored by University Medical Center Groningen
Actively Recruiting
SponsorUniversity Medical Center Groningen
Started2023-02-01
Est. completion2025-06
Eligibility
Age18 Years – 100 Years
View on ClinicalTrials.gov →

NCT06366828

Summary

The aim of this project is to develop and validate NTCP-models for complications after nCRT (and surgical resection), that can be uses for model-based dose optimization for PhRT and PRT, and for model-based selection for PRT, in patients with esophageal cancer

Eligibility

Age: 18 Years – 100 Years
Inclusion Criteria:

* Tumor in the esophagus, histologically proven or suspect for esophageal carcinoma
* WHO performance 0-2
* Age\>18years
* No distant metastasis (M0)
* Treated with nCRT and planned for or followed by an esophagectomy between 2015 and 2021 in one of the participating centers.

Exclusion Criteria:

* Sarcoma, neuro-endocrine or small cell carcinoma of the esophagus
* Patients who underwent a surgical resection in a non-participating surgical center will be excluded

Conditions2

CancerThe Aim of This Project is to Develop and Validate NTCP-models for Complications After nCRT (and Surgical Resection)

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