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A Proteomic Analysis for Understanding the Link Between Migraine and Cardiovascular Disease

RECRUITINGSponsored by Centro Cardiologico Monzino
Actively Recruiting
SponsorCentro Cardiologico Monzino
Started2024-04-03
Est. completion2025-10-30
Eligibility
Age25 Years – 60 Years
View on ClinicalTrials.gov →

NCT06372509

Summary

This is a multicenter, prospective observational study. Will be collecting data from 90 consecutive patients (aged 25- 60 years ) with and without migraine admitted at our Hospital. Primary aim of the study will be to assess the correlation between migraine and proteomic profiling of plasma and their possible correlation with known cardio and cerebrovascular disease and Cardiovascular (CV) risk factors.

Eligibility

Age: 25 Years – 60 Years
Inclusion Criteria:

* Age \>25 years and \> 60 years
* Signed patient informed consent form (ICF)
* Non-coronary disease

Exclusion Criteria:

* Age \< 25 years and \> 60 years
* Acute myocardial infarction (MI)
* Chronic kidney disease: glomerular filtration rate (GFR) \< 30 ml/min
* Severe mitral or aortic valvular disease
* Acute heart failure
* Reduced left ventricular (LV) function (Ejection Fraction \< 35%)
* Atrial Fibrillation

Conditions4

Cardiovascular DiseasesCoronary Artery DiseaseHeart DiseaseMigraine

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