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Resistance Training and Corticospinal Excitability in Multiple Sclerosis

RECRUITINGN/ASponsored by University of Aarhus
Actively Recruiting
PhaseN/A
SponsorUniversity of Aarhus
Started2024-05-01
Est. completion2025-12-31
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06374108

Summary

The goal of the present study is to investigate effects of progressive resistance training on central nervous system functioning (corticospinal excitability (CSE)) and walking capacity in persons with multiple sclerosis (pwMS). A total of 54 pwMS will be enrolled and randomized into 1 of 3 groups: high dose resistant training (RT), low dose RT, and waitlist control.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Age ≥ 18 years
* MS diagnosis according to the McDonald diagnostic criteria
* Shows impairments in walking capacity
* Ability to self transport to test and exercise

Exclusion Criteria:

* Pregnancy
* Neurological or other comorbidities that affects the nervous system
* Relapse within the past 2 months
* Pacemaker or metallic implants
* Hypertension (medically unregulated)
* Participation in structured RT over the past 3 months (≥ 2 sessions/week).

Conditions1

Multiple Sclerosis

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