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Role of Calcium Chloride Injection in Alleviating Atrial Fibrillation Post CABG

RECRUITINGPhase 3Sponsored by Helwan University
Actively Recruiting
PhasePhase 3
SponsorHelwan University
Started2024-03-14
Est. completion2025-03
Eligibility
Age18 Years – 74 Years
Healthy vol.Accepted

Summary

This study hypothesize that injecting calcium chloride (CaCl2) into the major atrial ganglionated plexus (GPs) during on pump Coronary artery bypass graft (CABG) can reduce the incidence of Post operative Atrial fibrillation in the first 7 days after surgery.The study is designed to be prospective interventional study two armed RCT for on pump CABG patient. The intervention arm will be injected with Calcium chloride in the four major atrial ganglionic plexus The control arm will be injected with sodium chloride to determine the effect of Calcium chloride on Post CABG Atrial fibrillation

Eligibility

Age: 18 Years – 74 YearsHealthy volunteers accepted
Inclusion Criteria:

1\) Patients more than 18 years old 2 ) patients undergoing On pump CABG

Exclusion Criteria:

1. patients \>75 years of age
2. Patients with Pre operative Atrial fibrillation
3. Patients with Significant valvular disease

5\. Ejection fraction \<30% 6. Combined surgery of any kind 7. Congenital heart disease 8. Abnormal severe liver or kidney dysfunction. 9. Patients undergoing Off-pump CABG 10. Poorly controlled hyperthyroidism 11. Refusal to enrollment.

Conditions2

Atrial FibrillationHeart Disease

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