Intraoperative Dexmedetomidine and Coronary Artery Bypass Graft Surgery

Summary

This is a prospective randomized clinical trial designed to determine the effect of intraoperative dexmedetomidine administration on renal function after coronary artery bypass graft surgery.

Eligibility

Inclusion Criteria:

* Elective coronary artery bypass graft surgery
* Age over 18 years
* ASA score 3 or 4
* Voluntary consent of the patient to participate in the research

Exclusion Criteria:

* Emergency coronary artery bypass graft surgery
* Chronic renal failure with eGFR \<60 ml/min/1.73m2
* Left ventricular ejection fraction \<30%
* 2nd or 3rd degree atrioventricular block
* Use of nephrotoxic agents such as aminoglycoside antibiotics or contrast agents within the last 48 hours
* Previous heart surgery or kidney surgery
* Allergy to dexmedetomidine

Conditions2

Interventions1

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