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Effects of Tomato Consumption on Steatosis, Intestinal Function and Glucose and Lipid Metabolism in Subjects With NAFLD

RECRUITINGN/ASponsored by Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Actively Recruiting
PhaseN/A
SponsorAzienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Started2024-05-14
Est. completion2025-05-20
Eligibility
Age18 Years – 75 Years
Healthy vol.Accepted

Summary

The study in question is an interventional study with nutritional intervention. the aim of the study is to evaluate whether a diet enriched with tomatoes can have favorable effects on: * specific aspects associated with NAFLD, such as the degree of hepatic steatosis and fibrosis; * circulating levels of molecules correlated with the degree of generalized and hepatic inflammation and the blood concentrations of metabolic and cardiovascular risk factors associated with abdominal obesity; * intestinal barrier; * body composition; * intestinal microbiota; * symptoms of IBS (irritable bowel syndrome) in patients with NAFLD.

Eligibility

Age: 18 Years – 75 YearsHealthy volunteers accepted
Inclusion Criteria:

* Patients with BMI≤30;
* Diagnosis of hepatic steatosis, formulated on the basis of criteria

Exclusion Criteria:

* Patients with BMI \> 30;
* Presence of any pathology that could influence the presence of steatosis apart from the pathologies that represent inclusion criteria;
* Pregnancy or breastfeeding;
* Serious medical conditions that may compromise participation in the trial;
* People following a special diet.

Conditions3

IBSLiver DiseaseNAFLD

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