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RAPID-POP a Randomized Controlled Trial

RECRUITINGN/ASponsored by National Institute of Cardiovascular Diseases, Pakistan
Actively Recruiting
PhaseN/A
SponsorNational Institute of Cardiovascular Diseases, Pakistan
Started2024-05-15
Est. completion2024-11
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

Efficacy of the Pressure Optimization Protocol (POP) versus Conventional Stent Deployment Strategy during Primary PCI: An Open Label Randomized Clinical Trial The investigators will compare conventional rapid stent inflation/deflation during primary PCI with higher pressure and prolonged duration of stent deployment Study Hypothesis: The POP in stent deployment is superior to the conventional stent deployment approach with a significantly higher achievement of the TIMI III flow, significantly lesser occurrence of slow flow/no-reflow, and significantly higher rate of ST-Segment resolution during primary PCI.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Patients aged 18 years and above.
* Patients undergoing primary percutaneous coronary intervention (PCI) with stent implantation.
* Presence of significant coronary artery stenosis (greater than 70% diameter reduction) confirmed by angiography.

Exclusion Criteria:

* Patients with Killip class IV
* Patients with significant comorbidities such as end-stage renal disease or advanced liver disease which may interfere with the procedure or follow-up.
* Prior history of coronary artery bypass grafting (CABG).
* Refusal to give consent for study participation or procedure

Conditions2

Heart DiseaseMyocardial Infarction, Acute

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