RAPID-POP a Randomized Controlled Trial
NCT06430892
Summary
Efficacy of the Pressure Optimization Protocol (POP) versus Conventional Stent Deployment Strategy during Primary PCI: An Open Label Randomized Clinical Trial The investigators will compare conventional rapid stent inflation/deflation during primary PCI with higher pressure and prolonged duration of stent deployment Study Hypothesis: The POP in stent deployment is superior to the conventional stent deployment approach with a significantly higher achievement of the TIMI III flow, significantly lesser occurrence of slow flow/no-reflow, and significantly higher rate of ST-Segment resolution during primary PCI.
Eligibility
Inclusion Criteria: * Patients aged 18 years and above. * Patients undergoing primary percutaneous coronary intervention (PCI) with stent implantation. * Presence of significant coronary artery stenosis (greater than 70% diameter reduction) confirmed by angiography. Exclusion Criteria: * Patients with Killip class IV * Patients with significant comorbidities such as end-stage renal disease or advanced liver disease which may interfere with the procedure or follow-up. * Prior history of coronary artery bypass grafting (CABG). * Refusal to give consent for study participation or procedure
Conditions2
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NCT06430892