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One-Year Trajectory of Cognitive Changes in Patients With Late-life Depression in the Short Term

RECRUITINGSponsored by Fujian Medical University
Actively Recruiting
SponsorFujian Medical University
Started2023-06-01
Est. completion2024-08-01
Eligibility
Age60 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06447428

Summary

The purpose of this study was to investigate the one-year trajectory of cognitive change in elderly patients with depression, to explore the transfer characteristics and transfer rules of various states of cognitive impairment in patients, to predict the relevant risk factors of cognitive decline, and to find possible influencing factors affecting state change, so as to provide a theoretical basis and reference for subsequent targeted intervention research on geriatric depression.

Eligibility

Age: 60 Years+Healthy volunteers accepted
Inclusion Criteria:

1. meeting the criteria for major depression in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)
2. age at first onset ≥60 years
3. Informed consent

Exclusion Criteria:

1. Relevant past history affecting cognitive function: various types of stroke, traumatic brain injury, severe brain atrophy, mental abnormalities
2. Perennial alcohol addiction, or long-term use of various drugs that affect mental state
3. Survival time of malignant tumors and tumors
4. Patients with language, vision, and hearing impairments

Conditions2

DepressionLate-Life Depression

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