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Multimodal Assesment of Alzheimer Patients

RECRUITINGSponsored by Norwegian University of Science and Technology
Actively Recruiting
SponsorNorwegian University of Science and Technology
Started2024-07-01
Est. completion2030-12-29
Eligibility
Age65 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06448403

Summary

The goal of this study is to learn more about the changes in the brains of patients with cognitive impairment (MCI) and Alzheimer's Disease (AD). The main questions the study aims to answer are: 1. What findings can be used to earlier detect patients that will develop Alzheimers? 2. Which differences are seen between healthy and cognitively impaired patients? 3. Which differences are seen between patients with Alzheimers disease? Participants will undergo: * Cognitive tests * Magnetic resonance imaging (MRI) * Electroencephalography (EEG) * Blood sample collection * Fecal sample collection * A randomized group will undergo polysomnography analysis.

Eligibility

Age: 65 Years+Healthy volunteers accepted
Inclusion Criteria:

* MCI and AD according to relevant ICD-criterias.
* Control cohort is age and gender matched with other cohorts.

Exclusion Criteria:

* Uneligibility for any of the planned neuroimagery devices (MRI, EEG)
* AD diagnosis before the age of 65 (Early-onset AD).
* Brain tumor
* Traumtic head injury
* Earlier neurosurgery
* Other neyrodegenerative diseases (i.e Parkinson and ALS)
* Diseases related to inflammation and auto-immunity (i.e MS)

Conditions5

Alzheimer Disease, Late OnsetAlzheimer's DiseaseCognitive ImpairmentDementiaMild Cognitive Impairment

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