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Multimodal Magnetic Resonance Imaging in Evaluation of Diabetic Kidney Disease

RECRUITINGSponsored by Shengjing Hospital
Actively Recruiting
SponsorShengjing Hospital
Started2024-06-06
Est. completion2027-06-06
Eligibility
Age18 Years – 80 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06452862

Summary

The goal of this study is to investigate the value of noninvasive evaluation of multimodal magnetic resonance imaging in diagnosis and treatment of diabetic kidney disease (DKD). We aim to explore the feasibility of multimodal magnetic resonance imaging in the staging diagnosis of DKD, and establish a non-invasive method for evaluating the progression of DKD disease by combining imaging and biochemical indicators. Multimodal magnetic resonance examinations will be performed on diabetic patients with different stages as well as regular follow-up during treatment, in order to investigate the relationship between imaging findings and pathophysiological changes of the kidneys.

Eligibility

Age: 18 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

* Clinically diagnosed diabetic kidney disease (DKD)
* Age 18-80 years

Exclusion Criteria:

* Malignant tumor, active infection, or life expectancy \<1 year
* Pregnancy or lactation
* MRE contraindications (metal implants, claustrophobia, severe arrhythmia) or poor image quality
* eGFR \<15 mL/min/1.73m² or receiving renal replacement therapy
* Other primary kidney diseases or systemic diseases affecting renal function

Conditions2

DiabetesDiabetic Kidney Disease

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