Accurate Prostate Cancer Following Using Low-Field MRI (Low-PRISM)

Summary

This study compares the effectiveness of low-field MRI (0.55T) with high-field MRI (3T) in prostate cancer screening and image quality. It consists of three phases: optimizing the low-field MRI protocol with healthy volunteers, evaluating image quality in patients with metallic artifacts (like hip prostheses), and assessing low-field MRI in patients with suspicious prostate lesions found on high-field MRI.

Eligibility

Inclusion Criteria:

Work Package1 (WP): 0.55T MRI Protocol Development

* Healthy male volunteers aged 18 and above.
* Agree to be contacted for incidental findings
* Signed informed consent

WP2: 0.55T Prostate MRI with patients with metallic implant(s)

* Adult men (≥18 y.o) with 3T MRI reported as sub-diagnostic due to metallic implants
* Signed informed Consent

WP3: 0.55T Prostate MRI with patients with suspicious lesion(s)

* Adult men (≥18 y.o)
* PI-RADS 4/5 lesions detected on 3T MRI, schedules for targeted biopsy
* Signed informed consent

Exclusion Criteria:

WP1: 0.55T MRI Protocol Development

* Individuals with a history of prostate cancer
* MR Contraindications as listed in the MR Safety Screening form

WP2: 0.55T Prostate MRI with patients with metallic implant(s)

* Contraindications as per MD instructions
* Any condition making the patient unsuitable for the study
* Refusal to be notified in case of incidental finding on the examination

WP3: 0.55T Prostate MRI with patients with suspicious lesion(s)

* Individuals with a history of prostate cancer.
* Contraindications as per MD instructions
* Any condition making the patient unsuitable for the study
* Refusal to be notified in case of incidental finding on the examination

Conditions2

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