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Extended Perioperative Administration of Fibrinolysis Inhibitors After Cardiac Surgery

RECRUITINGN/ASponsored by Saint Petersburg State University, Russia
Actively Recruiting
PhaseN/A
SponsorSaint Petersburg State University, Russia
Started2024-08-01
Est. completion2025-12-30
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06493227

Summary

PRIORITY is a pragmatic, multi-center, cluster crossover trial that aims to evaluate whether implementing a policy of routine extended (intraoperative and 4 hour after transfer to ICU) use of fibrinolysis inhibitors leads to a decrease in post-operative blood transfusion compared to a policy that only involves intraoperative use.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

1. A hospital that performs a minimum of 250 open heart interventions per year.
2. Consent from hospital physicians regarding the prophylactic use of fibrinolysis inhibitors (more than 95% of physicians involved in the treatment of adult patients (\>18 years) agree to adhere to the strategy of using fibrinolysis inhibitors as prescribed by the study protocol).

Exclusion Criteria:

* Hospital does not meet inclusion criteria

Conditions4

Fibrinolysis ShutdownHeart DiseaseHeart DiseasesThoracic Surgery

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