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Coronary Microvascular Dysfunction in Angina Patients With Non-obstructive Coronary Artery Disease (ANOCA-CMD)

RECRUITINGSponsored by China-Japan Friendship Hospital
Actively Recruiting
SponsorChina-Japan Friendship Hospital
Started2023-07-01
Est. completion2024-12-31
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06503640

Summary

The goal of this observational study is to explore the incidence and effect on prognosis of coronary microvascular dysfunction in patients present of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) \>0.80.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* presence of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) \>0.80

Exclusion Criteria:

1. acute myocardial infarction
2. significant valvular heart disease
3. advanced chronic kidney disease
4. patients with significant epicardial coronary artery stenosis (\>70% in major vessels by diagnostic coronary angiography) needing percutaneous coronary intervention
5. patients unable to provide written informed consent

Conditions4

Angina Patients With Non-obstructive Coronary Artery DiseaseCoronary Microvascular DysfunctionHeart DiseaseIndex of Microvascular Resistance

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