Eccentric Exercise and Fatigue in Multiple Sclerosis

Summary

The goal of this observational study is to compare the impact of eccentric resistance training to traditional resistance training on fatigue in persons with multiple sclerosis (MS). The primary question this study is asking is the following: is eccentric resistance training more fatiguing than traditional resistance training in persons with MS?. Participants will be asked to come for two sessions for two weeks. In the first week, subjects will undergo a bout of either traditional or eccentric resistance training. The next day they will return to assess their level of fatigue. The following week the subject will return and undergo whatever type of training they did not experience the first week, and it's effects on fatigue will again be assessed. The difference between the subjects level of fatigue for either condition will be compared.

Eligibility

Inclusion Criteria:

* Definitive diagnosis of Multiple Sclerosis.
* Ability to walk for 6 minutes continuously with or without assistive device
* Ability read, understand and sign and informed consent

Exclusion Criteria:

* Evidence of recent exacerbation in the last 2 months prior to starting the study
* Orthopedic, cardiopulmonary, or non -MS neurologic condition that could interfere with carrying out the study protocol

Conditions2

Locations1 site

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