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Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia

RECRUITINGSponsored by University Hospital, Toulouse
Actively Recruiting
SponsorUniversity Hospital, Toulouse
Started2026-04-07
Est. completion2027-10-07
Eligibility
Age12 Years – 18 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06506734

Summary

The main objective of this study is to assess the prevalence of dental discoloration (dental dyschromia) in children who experienced high levels of bilirubin in their blood (hyperbilirubinemia) during their early years. The study will also examine risk factors associated with this condition, such as the duration and severity of hyperbilirubinemia, underlying diseases, and treatments received. The researchers hypothesize that the quality of life of individuals with dental dyschromia is lower than that of individuals without dyschromia. The results of this study will be used to discuss coverage for dental care with health insurance for children affected by this condition.

Eligibility

Age: 12 Years – 18 YearsHealthy volunteers accepted
Inclusion Criteria:

* A patient with biliary atresia, progressive familial intrahepatic cholestasis, or Alagille syndrome
* Patient or legal representative not opposed to participating in this research.

Exclusion Criteria:

* Inability to understand and respond to quality of life questionnaires

Conditions3

Dental DiseasesHeart DiseaseLiver Disease

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