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Comparative Study of CT and Fluoroscopic Guided Genicular Nerve Ablation in the Treatment of Knee Osteoarthritis

RECRUITINGN/ASponsored by Zagazig University
Actively Recruiting
PhaseN/A
SponsorZagazig University
Started2024-09-29
Est. completion2025-04-30
Eligibility
Age45 Years – 80 Years
Healthy vol.Accepted

Summary

The goal of this study is to evaluate the comparative effectiveness of CT-guided and fluoroscopic-guided genicular nerve ablation in reducing knee pain and improving function in adults diagnosed with knee osteoarthritis refractory to conservative treatment. The main questions it aims to answer are: * Does CT-guided genicular nerve ablation provide superior pain relief compared to fluoroscopic-guided genicular nerve ablation? * Is there a significant difference in functional improvement between the two techniques? Researchers will compare the outcomes between the CT-guided and fluoroscopic-guided groups to determine which method achieves better pain relief, functional enhancement, safety profile, and patient satisfaction. Participants will: * Undergo either CT-guided or fluoroscopic-guided genicular nerve ablation. * Attend scheduled follow-up visits to assess pain levels, knee function, and any adverse events. * Complete standardized questionnaires to provide feedback on pain relief, functional improvement, and overall satisfaction with the procedure.

Eligibility

Age: 45 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

* Adults aged 45 to 80 years.
* Diagnosed with knee osteoarthritis.
* Knee osteoarthritis refractory to conservative treatment.
* Able to provide informed consent.
* Agree to follow the study procedures and attend follow-up visits.

Exclusion Criteria:

* Prior knee surgery within the last six months.
* Contraindications to genicular nerve ablation (e.g., certain types of infections, bleeding disorders).
* Severe comorbid conditions that may interfere with the study outcomes (e.g., rheumatoid arthritis, other severe autoimmune diseases).
* Current participation in another clinical trial that could interfere with the outcomes of this study.
* Allergy or sensitivity to the materials used in the ablation procedures.

Conditions2

ArthritisOsteoarthritis, Knee

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