Study on the Classification of Comprehensive Treatment Effect of Hepatocellular Carcinoma

Summary

Through a retrospective study of patients who underwent comprehensive treatment for hepatocellular carcinoma at the Second Affiliated Hospital of Zhejiang University, we explored the risk factors related to the sensitivity of comprehensive treatment. We used the PD-L1 expression level of patients before comprehensive treatment，characteristic morphology of tertiary lymphoid structures, as well as other parameters, are used to construct a liver cancer comprehensive treatment efficacy evaluation model. Using this liver cancer comprehensive treatment efficacy evaluation model, we conducted a randomized controlled trial on whether to receive comprehensive treatment for liver cancer patients to verify the accuracy and practical value of the model.

Eligibility

Inclusion Criteria:

* Patients with advanced hepatocellular carcinoma

Exclusion Criteria:

* Have comorbidities of severe diabetes, heart failure, liver and/or kidney failure
* Have a history of schizophrenia
* Have a history of other malignant tumors or metastatic liver tumors discovered after surgery
* Received anti-tumor drugs for other diseases
* Special groups such as pregnant and lactating women.

Conditions5

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