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Prostate Adaptive Radiation Therapy

RECRUITINGN/ASponsored by Royal North Shore Hospital
Actively Recruiting
PhaseN/A
SponsorRoyal North Shore Hospital
Started2025-10-01
Est. completion2029-10-31
Eligibility
Age18 Years+
SexMALE
Healthy vol.Accepted

Summary

Prostate ART is a two phase study looking at using adaptive radiotherapy to help reduce toxicity for prostate cancer patients. Adaptive radiotherapy is a new technology that provides the ability to account for daily changes in anatomy. Adaptive radiotherapy also provides a foundation for which radiotherapy margins might be safely reduced. Phase 1 of this study is looking to see if a radiation therapist centred adaptive workflow can be implemented. If phase 1 of this study is safe and feasible, the study will proceed to phase 2. Part 2 of the study looks at using adaptive technology to reduce radiation treatment margins. The primary aim of this study is to see whether margin reduced treatment using adaptive radiotherapy can reduce side effects for prostate cancer patients.

Eligibility

Age: 18 Years+Sex: MALEHealthy volunteers accepted
Inclusion Criteria:

1. \- Age \> 18
2. Biopsy proven prostate malignancy
3. Definitive treatment is radiotherapy to the prostate alone
4. ECOG performance status 0-2
5. Ability to understand and the willingness to sign an informed consent

Exclusion Criteria:

1. Hip prosthesis
2. Patient separation from prostate centre to skin edge \> 24cm, measured on diagnostic scan-

Conditions2

CancerProstatic Neoplasms

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