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Cardiotoxicity of Carbon Monoxide in Patients Treated With Hyperbaric Oxygen Therapy

RECRUITINGSponsored by University Hospital, Brest
Actively Recruiting
SponsorUniversity Hospital, Brest
Started2022-07-25
Est. completion2022-10-25
Eligibility
Age18 Years – 100 Years
View on ClinicalTrials.gov →

NCT06549621

Summary

Carbon monoxide poisoning is a frequent domestic accident and the leading cause of death from unintentionnal poisoning. Its toxicity is based on the CO binding to hemoglobin and myoglobin, inhibition of mitochondrial cytochrome oxidase, resulting in tissue hypoxia and reduced adenosine triphosphate synthesis and ischemia-reperfusion injury. This study aims to investigate the early and late cardiologic effects of CO in patients treated with hyperbaric oxygen (HBOT) for CO poisoning

Eligibility

Age: 18 Years – 100 Years
Inclusion Criteria:

Patients treated for CO poisoning with HBOT in the hyperbaric and underwater medicine department of the Brest University hospital from 2015/01/01 to 2021/12/31

Exclusion Criteria:

* refusal

Conditions2

Carbon Monoxide PoisoningHeart Disease

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