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Analysis of Protein Expression in Serum of KOA Subjects

RECRUITINGN/ASponsored by China Medical University Hospital
Actively Recruiting
PhaseN/A
SponsorChina Medical University Hospital
Started2024-08-04
Est. completion2025-07-23
Eligibility
Age50 Years+
Healthy vol.Accepted

Summary

In the previous study "Using omics technology to explore the mechanism of acupuncture treatment of different acupoints of knee osteoarthritis: a randomized controlled trial (CMUH109-REC3-113)", we found that acupuncture for knee osteoarthritis(KOA) significantly reduces inflammation, apoptosis, and metabolism-related serum protein profiles. However, due to the lack of serum protein data from the control group, it is impossible to establish standard values for comparison. To analyze the protein expression in the serum of KOA control group subjects, we also measured the spectral energy values of the radial artery pulse wave obtained from the pulse sphygmograph and the meridian energy values obtained from Ryodoraku. The results obtained can be compared with previous studies, thus this experiment was designed.

Eligibility

Age: 50 Years+Healthy volunteers accepted
Inclusion Criteria:

* Adults over 50 years old without knee pain

Exclusion Criteria:

1. Clinical diagnosis of knee osteoarthritis
2. Taking anti-inflammatory and analgesic drugs in the past month
3. Taking blood-lipid-lowering drugs or health foods in the past month
4. Received any acupuncture treatment in the past 3 weeks

Conditions2

ArthritisKnee Osteoarthritis

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