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Testicular Function and Semen Quality in Male Childhood and Adolescent Cancer Survivors

RECRUITINGSponsored by The University of Hong Kong
Actively Recruiting
SponsorThe University of Hong Kong
Started2023-01-16
Est. completion2027-12-31
Eligibility
Age18 Years – 50 Years
SexMALE
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06587477

Summary

Cancer treatment can affect the testicular function, including sperm and hormonal functions. The aim of this study is to assess the testicular function and semen quality in young men who recover from childhood and adolescent cancer in Hong Kong. This can provide more information for pre-treatment counselling as well as improve post treatment survivorship care. The testicular function will be compared to aged-matched controls from men attending the Family Planning Association for premarital check-up.

Eligibility

Age: 18 Years – 50 YearsSex: MALEHealthy volunteers accepted
Inclusion Criteria:

* Men who have received chemotherapy and/ or radiotherapy for cancer diagnosed when they were \< 18 years old.
* \> 18 years old to 50 years old
* Cancer in remission for at least 2 years

Exclusion Criteria:

* Unable to ejaculate by masturbation to provide semen samples
* Cryptorchidism, testicular cancer, history of vasectomy
* On testosterone replacement therapy
* Refusal to join the study

Conditions4

CancerCancer, Treatment-RelatedLate EffectSemen Analysis

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