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Factors for the Onset and Course of Axial Spondylitis

RECRUITINGSponsored by Karolinska Institutet
Actively Recruiting
SponsorKarolinska Institutet
Started2022-09-01
Est. completion2035-12-31
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

In a research project, investigators want to study the course of the disease of axial spondylitis: the causes of disease onset, prognosis, and treatment effects. The goal is to improve treatment and in the long run also prevention of the disease. The project has a focus on the body\'s own substance prostaglandin, and its proinflammatory role in spondylitis, but also other substances may be analyzed in blood and urine samples. The purpose of the research project is include newly diagnosed treatment-naive patients with axial spondyloarthritis, to follow them after 1 and 2 years after treatment start, to collect clinical data, questionnaires, blood and urinsamples to find blood or urine markers that can be used for precision therapy of axial spondylitis.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* newly diagnosed patients with axial spondyloarthritis
* treatment-naive
* 18 years of age or older
* Swedish-speaking
* Able to give informed consent

Exclusion Criteria:

* DMARD treatment,
* ongoing infection
* ongoing malignancy

Conditions2

ArthritisAxial Spondyloarthritis

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