Prospective Observational Cohort Study of Moderate Aortic Valve Disease

Summary

The objective of this research is to evaluate and predict the progression of moderate aortic stenosis and regurgitation from clinical characterization, biological, echocardiographic, and computed tomography (CT) et. al. Additionally, try to analyze the potential impact of device or drug therapy on the progression of the conditions.

Eligibility

Inclusion Criteria:

* At least 18 years old
* Be willing and able to provide informed consent to participate in the study
* Patient has moderate aortic valve diseases with echocardiographically derived criteria

Exclusion Criteria:

* Severe aortic valve diseases with echocardiographically derived criteria or planned cardiac surgery or likely need for surgery within 6 months
* Patients who have undergone elective transfemoral transcatheter aortic valve replacement
* Life expectancy is less than 12 months due to non-heart disease (such as cancer, chronic liver disease, chronic kidney disease, or chronic end-stage lung disease, etc.)
* Severe dementia (cannot sign research informed consent, cannot take care of themselves or complete the study visit)
* Acute pulmonary oedema or cardiogenic shock
* The investigator believes that the patient is not suitable to participate in the study or complete the follow-up prescribed by the protocol from other medical, social and psychological aspects
* The patient is currently participating in another randomized study

Conditions4

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