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Cardiac Assessment and Takotsubo-stunning Among COPD-exacerbations In-Hospital

RECRUITINGSponsored by Sahlgrenska University Hospital
Actively Recruiting
SponsorSahlgrenska University Hospital
Started2024-09-23
Est. completion2026-12-31
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06597331

Summary

The goal of this prospective observational study is to investigate to what extent acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) triggers Takotsubo-stunning, and how this affects the outcome for these patients. The main questions it aims to answer are: 1. What is cumulative incidence of Takotsubo-stunning in patients hospitalized for AE-COPD at Sahlgrenska University Hospital/S (Gothenburg, Sweden)? 2. Among patients hospitalized for AE-COPD at Sahlgrenska University Hospital/S, what is the risk of in-hospital clinical manifestations of acute heart failure in patients with Takotsubo-stunning compared to those without?

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Adult patients (≥ 18 years old) admitted to hospital ward for AE-COPD
* Inclusion within 72 hours of admission,
* Written informed consent

Exclusion Criteria:

* Prior acute myocardial infarction or known pre-existing persistent regional wall motion abnormality or left ventricular dysfunction (left ventricular ejection fraction \[LVEF\] \<50%)
* Expected inability to comply with the protocol (e.g. dementia)

Conditions5

Acute Heart FailureCOPDChronic Obstructive Pulmonary DiseaseHeart DiseaseTakotsubo Cardiomyopathy

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