Monitoring and Optimization of Cerebral Perfusion Pressure in Post-cardiac Arrest Patients: a Pilot Study

Summary

The goal of this study is to establish the ICP and CPP monitoring process and analyze the results in post-arrest patients, to validate the correlation between direct and non-invasive ICP monitoring indicators, to establish a protocol of management of elevated ICP and insufficient CPP in post-arrest care, to establish a protocol for personalizing CPP and MAP optimization, and to analyze its impact on neuroprognosis. Participants will receive ICP monitoring within 12 hours post-ROSC if meet all inclusion and exclusion criteria.

Eligibility

Inclusion Criteria:

* non-traumatic cardiac arrest
* admitted to ICU
* GCS: motor \<=5
* severity: TIMECARD score medium-risk group

Exclusion Criteria:

* traumatic cardiac arrest
* pregnancy
* intracranial hemorrhage
* coagulopathy
* anti-platelet or anti-coagulation use
* terminal illness
* pre-arrest CPC score \>=3
* GWR \< 1.2 on CT or severe hypoxic ischemic encephalopathy
* CNS infection

Conditions2

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