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Tumor-Informed ctDNA Testing for MRD Following Treatment of Squamous Cell Carcinoma

RECRUITINGSponsored by University of California, San Francisco
Actively Recruiting
SponsorUniversity of California, San Francisco
Started2024-10-09
Est. completion2028-12-30
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT06606028

Summary

This is a single-center, non-interventional, observational study that evaluates the correlation of circulating tumor DNA (ctDNA) testing to cancer relapse for participants with squamous cell carcinomas (HNC) of the head and neck mucosa and skin after curative-intent primary radiation or surgery.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

1. Participants must have histologically or cytologically confirmed squamous cell carcinoma of the head and neck mucosa and skin.
2. Participants must be age \>=18 years.
3. Participants must be planning to receive curative-intent surgery or radiation-based treatment as part of standard of care treatment.
4. Participants must have the ability to understand and the willingness to sign a written informed consent document.

Exclusion Criteria:

1\. Contraindication to phlebotomy for removal of 20 mL of peripheral blood each time point (up to 300 mL total over 15 time points).

Conditions5

CancerCutaneous Squamous Cell Carcinoma (CSCC)Squamous Cell Carcinoma Head and Neck Cancer (HNSCC)Squamous Cell Carcinoma of Head and NeckSquamous Cell Carcinoma of Skin

Locations1 site

University of California, San Francisco
San Francisco, California, 94143
Sonia Contreras Martinez415-514-6427

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