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Development of Tumor Organoids From Undifferentiated Primary Carcinomas to Guide Therapeutic Decisions

RECRUITINGSponsored by Centre Francois Baclesse
Actively Recruiting
SponsorCentre Francois Baclesse
Started2025-03-05
Est. completion2028-12-15
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06612827

Summary

The study is based on the constitution of a collection of tumor and blood samples for the development of tumoroid for functional tests to predict clinical response to treatment.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Patient with undifferentiated primary carcinoma (UPC) with histological and immunohistochemical evidence, validated in a local and/or national UPC multidisciplinary consultation
* Patient with indication for systemic 1st-line treatment at the time of inclusion. Treatment may already have begun at the time of inclusion, but within the limit of 2 treatment cycles administered.
* Patient with life expectancy greater than 3 months
* Patient of legal age
* Patient affiliated to a social security scheme
* Signature of informed consent prior to any specific study procedure

Exclusion Criteria:

* Persons deprived of their liberty or under guardianship (including curatorship)
* Pregnant or breast-feeding patient

Conditions2

CancerUndifferentiated Carcinoma

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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