Partial Prostatectomy for Prostate Cancer

Summary

A phase 2 study investigation of safety and feasibility of partial prostatectomy for localized prostate cancer of intermediate risk at ICESP. It will be included 50 patients that have coincident findings of prostate cancer site on prostate biopsy and a suspicious area in the magnetic resonance imaging of the prostate (PIRADS 3, 4 or 5).

Eligibility

Inclusion Criteria:

Patients with prostate cancer that presents an institutional (ICESP) fusion biopsy (cognitive or target) that presents

1. Fusion-guided prostate biopsy with mpMRI performed at the São Paulo State Cancer Institute, which
2. Present fragments for ISUP group grade (GG) ≤ 3 in only one of the prostate lobes
3. Multiparametric prostate resonance with PIRADS 3 - 5 and which is in agreement with the laterality of the tumor in the prostate biopsy
4. Life expectancy ≥ 10 years according to the Charlson score
5. Absence of second primary cancer under active treatment. Patients treated for cancer from other sites for more than 5 years and without evidence of disease will be allowed
6. Able to read, understand and complete the informed consent related to the research, as well as the research questionnaires on quality of life and functional parameters on erection and urinary continence

Exclusion Criteria:

1. Patients with prostate cancer with an histology different from adenocarcinoma
2. Suspicion of lymph node metastasis on mpMRI or distant bone scintigraphy
3. definitive signs of extraprostatic extension on mpMRI
4. history of pelvic/prostatic radiotherapy
5. ISUP grade group ≥ 4
6. Laterality of prostate biopsy discordant with mpMRI findings

Conditions2

Browse More Trials