Comparison of Intralipid With SMOF Lipid Following HSCT

Summary

The goal of this clinical trial is to have a successful engraftment in after bone transplantation. Acute leukemia patient of both sexes aged 2 to 18 years, who are transplant candidates, participate in this study. Primary hypothesis is Patients receiving SMOF LIPID will have better grafts than patients receiving intralipid. Also, complications after surgery and malnutrition will be less in this group.

Eligibility

Inclusion Criteria:

* Willingness to cooperate and complete the informed consent form by the legal guardian of the child;
* Age ≤ 18 years;
* Definitive diagnosis of acute leukemia and candidate for hematopoietic stem ● cell transplantation;
* Eligible for parenteral nutrition support;
* No contraindications for parenteral nutrition;
* No history of allergy to egg or soy protein;
* Absence of severe organ failure or impaired liver function test (bilirubin \> 2.5 mg/dL).

Exclusion Criteria:

* Death of the child earlier than 5 days from the start of the intervention;
* Unwillingness to continue cooperation during study;
* Occurrence of side effects during the study;
* In case of sepsis, hypotension, shock, thrombosis, myocardial infarction, liver dysfunction, the patient will be excluded from the study.

Conditions3

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