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Fast and Accurate Breast Cancer Diagnosis Using Nanopore Sequencing in Tanzania (Fast-ABCD Sequencing)

RECRUITINGSponsored by University of Bonn
Actively Recruiting
SponsorUniversity of Bonn
Started2025-05
Est. completion2026-04
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

This pilot study will test the feasibility of using nanopore sequencing for breast cancer diagnosis in Tanzania. It aims to show that nanopore sequencing is non-inferior to the current standard of care, with the potential for faster and more cost-efficient results. By enhancing the speed and accuracy of diagnosis, this approach could improve treatment planning and outcomes for patients in resource-limited settings.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Patient with suspected diagnosis of breast cancer undergoing biopsy or surgical resection after specialist consultation as per institutional guidelines
* Excess fresh tumor sample
* Written informed consent

Exclusion Criteria:

* Unable to provide informed consent
* Patients who have already commenced therapy for BC (except for treatment other than biomedicine, e.g. herbal medicines)

Conditions3

Breast CancerBreast Cancer InvasiveCancer

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