Comparison Between Whole Body DWI and FDG PET/CT in Patients with Simptomatic Multiple Myeloma

Summary

The primary objective is to evaluate the concordance of FDG PET/CT and total body DWI MRI sequences performed during staging and at the completion of therapy. Specifically, we will assess the positivity rates, both patient-based and lesion-based (total and by district), of the two methods during staging and at the completion of therapy. An interim analysis will be conducted comparing the two methods, followed by a final prognostic analysis.

Eligibility

Inclusion Criteria:

* • Patients with symptomatic myeloma in the staging phase or with suspected symptomatic myeloma in the diagnostic phase

  * Patients who have signed the informed consent form

Exclusion Criteria:

* Patients simultaneously affected by other neoplastic diseases or with a history of other neoplasms in the previous 5 years

  * Age \< 18 years
  * Women who are breastfeeding or pregnant
  * Patients with metal implants or devices that constitute an absolute contraindication for MRI
  * Patients with severe claustrophobia
  * Patients with bone pain that prevents prolonged maintenance of the supine position

Conditions2

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