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GYNecologic Cancer-Related COGnitive Impairment

RECRUITINGN/ASponsored by Northwestern University
Actively Recruiting
PhaseN/A
SponsorNorthwestern University
Started2025-02-07
Est. completion2027-12
Eligibility
Age18 Years+
SexFEMALE
Healthy vol.Accepted
Locations1 site

Summary

The goal of this study is to test a home-based and patient-tailored cognitive training intervention among gynecologic cancer patients who have completed chemotherapy and who have experienced cancer-related cognitive impairment.

Eligibility

Age: 18 Years+Sex: FEMALEHealthy volunteers accepted
Inclusion Criteria:

* Female; ≥18 years of age
* Presents to clinic with a confirmed diagnosis of a gynecologic cancer (e.g., ovarian, endometrial, cervical, or vulvar cancer) who have completed adjuvant chemotherapy with at least stable disease at time of screening.
* Screen positive for subjective cognitive impairment by answering affirmatively to at least one of three screener questions
* Fluent in spoken and written English
* Have access to the internet to complete assessments

Exclusion Criteria:

* Patients who have not received chemotherapy
* Patients with pre-existing neuropsychiatric disorders that would impact cognitive function, such as dementia, Alzheimer's disease, and schizophrenia.
* Patients with non-gynecologic causes of incurable metastatic cancers.
* Patients undergoing active interventions in other cognitive trials or patients currently using cognitive training programs such as Brain HQ, Luminosity, Elevate, Peak, Fit Brains, or CogniFit.
* Patients with self-report of learning disability or an unwillingness to participate in technology-based cognitive training programs.
* Pregnant women or prisoners
* Patients with impaired-decision making capacity

Conditions8

CancerCervical CancersCervix CancerEndometrial CancerOvarian CancerOvary CancerUterine CancerVulvar Cancers

Locations1 site

Northwestern University
Chicago, Illinois, 60611
Anne Grace, PhD312-503-4165anne@northwestern.edu

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