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Non-Invasive Programmed Stimulation (NIPS) to Guide the Subsequent VT Therapeutic Strategies

RECRUITINGN/ASponsored by IRCCS Ospedale San Raffaele
Actively Recruiting
PhaseN/A
SponsorIRCCS Ospedale San Raffaele
Started2025-06-12
Est. completion2027-12
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06669299

Summary

The aim of this study is to define the importance of non-invasive programmed stimulation (NIPS) in risk stratification of ventricular tachycardia (VT) recurrence after catheter ablation and to determine the optimal treatment strategy. The primary objective is to establish whether a new VT ablation based on NIPS inducibility will reduce the risk of VT recurrence compared to antiarrhythmic drug therapy.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Patients with an implanted ICD (all brands)
* Patients who underwent a successful (non-inducibility of any VT) Ventricular Tachycardia Ablation procedure, the "index procedure", supported by EnSite Precision or CARTO 3D mapping systems for the following etiologies: previous MI, myocarditis, ARVD, IDCM.
* Induction of monomorphic VT at NIPS 3-7days after a successful index procedure
* Age 18 years or more
* Able to provide an informed consent to participate to the study and available to respect the assessments described in the protocol.

Exclusion Criteria:

* Inducible VT after index procedure
* Contraindication to anticoagulants
* Presence of thrombi
* Presence of Mitral and Aortic prosthetic valve
* Recent (\<3 months) myocardial infarction or unstable angina or Coronary Artery Bypass
* Pregnant or nursing
* Ventricular Tachycardia caused by reversible pathology
* \< 1 Year life expectancy according to the investigator

Conditions2

Heart DiseaseVentricular Tachycardia (VT)

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