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Effects of Partial Sleep Deprivation on Cardiac Output During Cycling

RECRUITINGN/ASponsored by University of Guelph
Actively Recruiting
PhaseN/A
SponsorUniversity of Guelph
Started2025-01-02
Est. completion2025-06
Eligibility
Age18 Years – 50 Years
Healthy vol.Accepted

Summary

The goal of this clinical trial is to determine if attenuations in cardiac output drive the blunted blood pressure response during cycling exercise following a night of partial sleep deprivation in young healthy adults (%50 females). The secondary outcome is to assess sex differences. The main questions it aims to answer are: * Do reductions in plasma volume drive reductions in cardiac output and therefore blood pressure during exercise following a night of partial sleep deprivation? * Do sex differences exist? Participants will: * Visit the lab after a night of normal sleep and a night of partial sleep deprivation. * Keep a daily diary of their sleep and food/beverage intake. * Perform maximal and submaximal exercise on a cycle ergometer.

Eligibility

Age: 18 Years – 50 YearsHealthy volunteers accepted
Inclusion Criteria:

* Free of known cardiovascular or metabolic diseases or sleep disorders
* No history of smoking (within the past 3 months)
* Able to engage in physical activity assessed through the physical activity readiness questionnaire (PAR-Q+)
* No prescription of chronic medications other than oral contraceptives
* Able to abide by sleep protocols for all visits
* Individuals who are not allergic to ultrasound gel
* Individuals who are not pregnant

Exclusion Criteria:

* Individuals diagnosed with cardiovascular or metabolic disease or sleep disorders
* Has a history of smoking (within the past 3 months)
* Not ready to engage in physical activity as assessed by the PAR-Q+
* Individuals prescribed chronic medications other than oral contraceptives
* Unable to abide by sleep protocols for any testing visit
* Allergic to ultrasound gel
* Pregnancy

Conditions2

Heart DiseaseSleep Deprivation

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