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An Individualized Online Home-Based Exercise Program for Improving Symptoms in Gynecologic Cancer Survivors

RECRUITINGN/ASponsored by Emory University
Actively Recruiting
PhaseN/A
SponsorEmory University
Started2025-09-01
Est. completion2026-07-30
Eligibility
Age18 Years+
SexFEMALE
Healthy vol.Accepted
Locations4 sites

Summary

This clinical trial tests an individualized online home-based exercise program in gynecologic cancer survivors and its impact on gut microbiome (the bacteria and microorganisms that live in the digestive system) and symptoms such as pain, fatigue, sleep disturbance, depression, and cognitive impairment. These symptoms can significantly reduce the quality of life (QoL) and survival rate in this cancer population. Thus, promoting physical activity among cancer survivors may help mitigate these severe symptoms. Using online platforms such as Zoom can help participants access an individualized exercise program that meets their specific needs to engage in physical activity and decrease their symptom burden. Home-based exercise, by providing self-chosen time and location and low costs, can address some barriers to physical activity for cancer survivors. An individualized online home-based exercise program may be feasible, and may improve symptoms and quality of life in gynecologic cancer survivors.

Eligibility

Age: 18 Years+Sex: FEMALEHealthy volunteers accepted
Inclusion Criteria:

* Women aged ≥ 18 years old
* Previously diagnosed with gynecologic cancer (e.g., uterine, ovarian, cervical)
* Completed cancer treatment (chemotherapy or chemoradiation)
* Able to read and speak English
* Do not meet recommended exercise levels as defined by The American College of Sports Medicine

Exclusion Criteria:

* History of metastatic or other primary cancer
* Serious mental health conditions (e.g., bipolar disorder, schizophrenia, major depression)
* Certain chronic diseases (e.g., muscular-skeletal diseases that limit mobility, autoimmune diseases, uncontrolled diabetes, hypertension, renal disease (creatinine \> 2.5 mg/dL)
* Unable to read/speak English

Conditions2

CancerMalignant Female Reproductive System Neoplasm

Locations4 sites

Grady Health System
Atlanta, Georgia, 30303
Zahra A. Barandouzi, Ph.D.,MSN,RN404-544-9078zahra.barandouzi@emory.edu
Emory University Hospital Midtown
Atlanta, Georgia, 30308
Zahra A. Barandouzi, Ph.D.,MSN,RN404-544-9078zahra.barandouzi@emory.edu
Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia, 30322
Zahra A. Barandouzi, Ph.D.,MSN,RN404-544-9078zahra.barandouzi@emory.edu
Emory Decatur Hospital
Decatur, Georgia, 30033
Zahra A. Barandouzi, Ph.D.,MSN,RN404-544-9078zahra.barandouzi@emory.edu

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