Semmelweis Esophageal Cancer Study: Noninvasive Prognostic Parameters in Patients With Oesophageal and Esophagogastric Junction Cancer

Summary

The objective of this observational study was to gain a deeper understanding of the epidemiology of the disease in Hungary through a broad analysis of patients with new-onset esophageal-oesophageal-stomach junction tumors, and to identify key parameters that could potentially influence the outcome of the disease and are closely correlated with morbidity and mortality. The investigators' primary objective is to identify potential factors and conditions that could be influenced and modified to enhance the disease outcome. Main questions: 1. What are the measurable changes in performance, workload, nutritional status, cardiac function, mental status in the patients studied? 2. What is the time course of the changes during and after treatment? 3. Which pathological parameters are associated with disease outcome and which are potential points of intervention to improve the course of the disease? Patients will undergo a detailed physical and nutritional assessment, non-invasive imaging tests and several questionnaires in addition to the usual pre- and post-operative examinations.

Eligibility

Inclusion Criteria:

* Age over 18 years
* Diagnosis of new-onset esophageal, esophagogastric junction tumor
* Elective curative surgery (open/laparoscopic regardless of surgical technique)
* Patients who have not yet received oncological treatment for their present disease

Exclusion Criteria:

* Lack of consent
* Lack of cooperation
* Contraindications for some studies: If MR scan is contraindicated, cardiac MR scan is not performed

Conditions3

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