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Efficacy of Adenosine as Compared to Verapamil in Paroxysmal Supraventricular Tachycardia (pSVT) Patients

RECRUITINGPhase 3Sponsored by Rashid Latif Medical College
Actively Recruiting
PhasePhase 3
SponsorRashid Latif Medical College
Started2024-10-28
Est. completion2025-01-27
Eligibility
Age18 Years – 70 Years
Healthy vol.Accepted

Summary

Supraventricular tachycardia (SVT) is a term widely used to describe tachycardial dysrhythmias, paroxysmal SVT (PSVT) is a narrow term including only AV nodal re-entrant tachycardia (AVNRT) and atrioventricular re-entrant tachycardia (AVRT), both of which can cause discomfort and, in some cases, life-threatening symptoms. Usually Carotid sinus massage is done to lower the pulse rate and after the standard time specific verapamil dose is administered. In this study after carotid sinus massage Conventional Valsalva or modified Valsalva maneuver will be randomly applied. In case, the normal sinus rhythm (NSR) is not achieved then verapamil of or adenosine dose will be administered to the patients after after taking the consent.

Eligibility

Age: 18 Years – 70 YearsHealthy volunteers accepted
Inclusion Criteria:

* Stable SVT (not requiring cardioversion, fully conscious, maintaining systolic blood pressure of \>90mmHg)
* Alert enough and able to give consent
* Able to lie flat and non-painful legs during passive leg raising

Exclusion Criteria:

* Unstable SVT (Semiconscious, drowsy, breathless, systolic BP \<90mmHg)
* Not able to give consent
* Orthopnea causing inability to lie flat
* Atrial fibrillation/atrial flutter
* Recent MI (within last 7 days)
* Ongoing ischemia as indicated by chest pain or ST segment depression/elevation in ECG
* Aortic stenosis
* All trimesters of pregnancy

Conditions2

Heart DiseaseSupraventricular Tachycardia (SVtach)

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