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Assessment of FibbroScan in Diagnosing MASLD Among the Chinese Population With Obesity

RECRUITINGSponsored by The Third People's Hospital of Chengdu
Actively Recruiting
SponsorThe Third People's Hospital of Chengdu
Started2023-10-24
Est. completion2025-03-31
Eligibility
Age18 Years – 70 Years

Summary

The non-invasive evaluation of liver steatosis and fibrosis with FibroScan is a routinely procedure in clinical practice for people with obesity. However, there are still considerable uncertainties regarding the potential influence of confounding factors and the optimal application of cut-off values for obesity. The goal of this observational study is to learn about the optimal application of cut-off values of for Chinese people with obesity.

Eligibility

Age: 18 Years – 70 Years
Inclusion Criteria:

1. Patients aged 18 years or older who provided written informed consent
2. Patients who schedule to undergo bariatric surgery and a liver biopsy (LB) for the investigation of suspected MASLD
3. Patients who schedule to undergo FibroScan examination

Exclusion Criteria:

1. Patients with ascites or pregnant women
2. Patients with any active implantable medical device (such as a pacemaker or defibrillator)
3. Patients who have undergone liver transplantation
4. Patients with cardiac failure and/or significant valvular disease
5. Patients with haemochromatosis
6. Patients who have refused to undergo LB or blood tests
7. Patients with a confirmed diagnosis of active malignancy, or other terminal disease
8. Patients participating in another clinical trial within the preceding 30 days

Conditions2

Fatty Liver DiseaseLiver Disease

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