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Arterial Stiffness for Improved Prediction of Coronary Artery Disease by Coronary CT Angiography

RECRUITINGSponsored by Danderyd Hospital
Actively Recruiting
SponsorDanderyd Hospital
Started2023-10-24
Est. completion2025-03
Eligibility
Age30 Years – 70 Years
Healthy vol.Accepted

Summary

This study will evaluate the ability of device-estimated pulse wave velocity and machine learning methods to improve the prediction of potential symptomatic coronary artery disease

Eligibility

Age: 30 Years – 70 YearsHealthy volunteers accepted
Inclusion Criteria:

* Patients undergoing coronary computer tomography angiography to investigate stable suspected symptomatic coronary artery disease.
* Age 30 to \<70 years of age.

Exclusion Criteria:

* Known coronary artery disease (prior myocardial infarction, percutaneous coronary intervention, coronary artery bypass graft or any angiographic evidence of coronary artery disease ≥50% lesion in a major epicardial vessel).
* Known significant cardiac (\> moderate valvular disease, heart failure with reduced ejection fraction, hypertrophic cardiomyopathy, or congenital heart disease), or pulmonary condition which could explain symptoms.
* Known ongoing atrial fibrillation/flutter.
* No Swedish social security number.
* Unable to provide written informed consent.

Conditions5

Arterial StiffnessChest PainCoronary Artery DiseaseDyspneaHeart Disease

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