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Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure

RECRUITINGN/ASponsored by Georgia State University
Actively Recruiting
PhaseN/A
SponsorGeorgia State University
Started2024-09-17
Est. completion2025-12-01
Eligibility
Age45 Years – 65 Years
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT06735599

Summary

The purpose of the study is to determine the effectiveness of wild blueberries on cardiovascular health, cognitive function, and gut microbiota composition in non-Hispanic Black and White adults with elevated blood pressure.

Eligibility

Age: 45 Years – 65 YearsHealthy volunteers accepted
Inclusion Criteria:

* Individuals 45-65 years of age
* Diagnosis of elevated blood pressure or stage 1 hypertension (systolic blood pressure = 120-139 mmHg and/or diastolic blood pressure = 80-89 mmHg) for at least 6 months
* BMI 25-30 kg/m2 via anthropometric measurements.
* Ability to give consent

Exclusion Criteria:

* Allergies to berries
* Use of one hypertensive drug for less than three months
* Use of more than one anti-hypertensive drug, insulin, antibiotics, and anti-inflammatory drugs, active cancer, gastrointestinal, renal, cardiovascular, thyroid, and neurological disorders or severe head injury
* Smoking
* Alcohol consumption (\>2 drinks/day)
* Consuming antioxidant, probiotic, and prebiotic supplements
* Pregnant or lactating
* Participating in a weight loss program

Conditions18

AdultArterial StiffnessBody Composition MeasurementCaucasian WhitesCognitionDiabetesDietEndothelial Function (Reactive Hyperemia)FemaleGut Microbiome

Locations1 site

Georgia State University
Atlanta, Georgia, 30303
Rafaela Feresin, PhD404-413-1233berries@gsu.edu

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