Recompensation in Alcohol Related Hepatitis
NCT06740318
Summary
Genetic activity and metabolic changes may be part of the pathogenesis in alcohol related hepatitis. We do not know exactly how alcohol cessation affects liver functions and metabolism. The aim of this study is to assess the impact of alcohol cessation in patients with alcohol related hepatitis and gain knowledge of the metabolic and genetic functions of the liver during remission and recompensation from alcohol related hepatitis. The study will assess 1. The effect of alcohol cessation on the liver. 2. The biological mechanisms involved in healing after alvohol-cessation 3. The effect of motivational enhcament therapy in alcohol cessation after alcohol related hepatitis. 4. The metabolic changes of lipids and proteins in the liver Participants are offered motivational enhancement therapy and standard of care.
Eligibility
Inclusion Criteria: * Clinical suspicion of AH, supported by biochemistry (bilirubin 50 mmol/l or higher) and ultrasound or other imaging techniques. * Informed written consent. Exclusion Criteria: * People where the diagnosis of AH is questioned with reasonable doubt. * Withdrawal of informed consent. * Persons eligible for inclusion where the investigational program is delayed or not initiated within two months after the diagnosis of suspected AH. * Persons with hepatocellular carcinoma
Conditions2
Browse More Trials
Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.
This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.
NCT06740318