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40 Hz Transcranial Alternating Current Stimulation for Inducing Gamma Oscillations

RECRUITINGN/ASponsored by The National Brain Mapping Laboratory (NBML)
Actively Recruiting
PhaseN/A
SponsorThe National Brain Mapping Laboratory (NBML)
Started2024-06-01
Est. completion2025-02-01
Eligibility
Age50 Years – 85 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06740864

Summary

This study aims to compare the efficacy of different 40 Hz tACS protocols in entraining gamma oscillations, which are linked to various cognitive functions and play a significant role in cognitive impairments like Alzheimer's disease. Specifically, it examines the effects of 40 Hz tACS applied to frontal brain regions versus fronto-temporal regions on gamma oscillations and working memory in healthy elderly individuals.

Eligibility

Age: 50 Years – 85 YearsHealthy volunteers accepted
Inclusion Criteria:

* healthy elderly between 50-80 years of age
* normal or corrected to normal eye vision
* right-handed
* non-smokers
* at least 70 % accuracy in working memory training task

Exclusion Criteria:

* history of neurological or psychiatric disorders including seizures or epilepsy,
* Taking CNS, blood pressure and other medications
* having metal implants in the head and neck
* significant cognitive decline meassured by The Montreal Cognitive Assessment (MoCA)

Conditions3

Alzheimer DiseaseAlzheimer's DiseaseCognitive Decline

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