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68Ga-NK224 PET Imaging of PD-L1 Expression in Cancers

RECRUITINGSponsored by The First Affiliated Hospital of Xiamen University
Actively Recruiting
SponsorThe First Affiliated Hospital of Xiamen University
Started2023-12-31
Est. completion2025-12-31
Eligibility
Age18 Years – 90 Years
Healthy vol.Accepted

Summary

To evaluate the potential usefulness of 68Ga-NK224 positron emission tomography/computed tomography (PET/CT) for the evaluation of PD-L1 expression in primary and/or metastatic tumors, compared with histopathological results.

Eligibility

Age: 18 Years – 90 YearsHealthy volunteers accepted
Inclusion Criteria:

* (i) adult patients (aged 18 years or order);
* (ii) patients with newly diagnosed or previously treated malignant tumors (supporting evidence may include magnetic resonance imaging (MRI), CT, tumor markers and pathology report);
* (iii) patients who had scheduled 68Ga-NK224 PET/CT scans;
* (iv) patients who were able to provide informed consent (signed by participant, parent or legal representative) and assent according to the guidelines of the Clinical Research Ethics Committee.

Exclusion Criteria:

* (i) patients with non-malignant lesions;
* (ii) patients with pregnancy;
* (iii) the inability or unwillingness of the research participant, parent or legal representative to provide written informed consent.

Conditions3

CancerPD-L1Tumor

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