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Evaluation of Chronic Liver Disease Condition and Transplant Prognosis Assisted by Eye Biological Parameters

RECRUITINGSponsored by Zhongshan Ophthalmic Center, Sun Yat-sen University
Actively Recruiting
SponsorZhongshan Ophthalmic Center, Sun Yat-sen University
Started2022-03-01
Est. completion2025-12-30
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

This study investigates the correlation between ocular biological characteristics and overall conditions before and after liver transplantation by collecting ocular biological characteristics. Explore whether it is possible to construct a clinical prediction model for liver transplantation by incorporating ocular biometric features, in order to optimize disease management before and after liver transplantation.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

1. Age greater than or equal to 18 years old;
2. Late stage liver disease patients waiting for liver transplantation treatment, as well as patients with varying degrees of cirrhosis;
3. Can collect complete basic demographic information, liver function blood test indicators, liver pathology and imaging examination results;
4. Can cooperate with eye OCT, OCTA and other examinations, and obtain qualified examination parameters;
5. Voluntarily follow the clinical trial protocol and sign the informed consent form.

Exclusion Criteria:

1. History of other organ transplant surgeries;
2. History of intraocular laser treatment, medication injection, and surgery;
3. History of high myopia, glaucoma, and retinal choroidal related eye diseases;
4. History of major systemic diseases other than liver disease;
5. Individuals whose overall body and eye conditions cannot cooperate with eye examinations.

Conditions4

Diagnostic Techniques, OphthalmologicalLiver CirrhosesLiver DiseaseLiver Transplantation

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