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A Clinical Study of CHT102 in MSLN-Positive Advanced Pancreatic Cancer

RECRUITINGPhase 1Sponsored by Tianjin Medical University Cancer Institute and Hospital
Actively Recruiting
PhasePhase 1
SponsorTianjin Medical University Cancer Institute and Hospital
Started2024-12-25
Est. completion2027-12-24
Eligibility
Age18 Years – 70 Years
Healthy vol.Accepted

Summary

Evaluate the safety and efficacy of mesothelin-targeting UCAR-T cells in the treatment of mesothelin-positive advanced pancreatic cancer

Eligibility

Age: 18 Years – 70 YearsHealthy volunteers accepted
Inclusion Criteria:

1. Ability to understand and sign a written informed consent documen;
2. At the date of signing ICF, 18 \~70 years old, male or female;
3. Histopathological confirmed advanced or metastatic pancreatic cancer patients who have failed to standard treatment or intolerance with standard treatment;
4. Positive mesothelin expression;
5. At least one measurable lesion at baseline per RECIST version 1.1;
6. The expected survival time is more than 12 weeks;
7. ECOG 0-1 points;
8. Adequate organ functions.

Conditions2

Advanced Pancreatic CancersCancer

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