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A Clinical Study of CHT102 in MSLN-Positive Advanced Pancreatic Cancer
RECRUITINGPhase 1Sponsored by Tianjin Medical University Cancer Institute and Hospital
Actively Recruiting
PhasePhase 1
SponsorTianjin Medical University Cancer Institute and Hospital
Started2024-12-25
Est. completion2027-12-24
Eligibility
Age18 Years – 70 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →
NCT06760364
Summary
Evaluate the safety and efficacy of mesothelin-targeting UCAR-T cells in the treatment of mesothelin-positive advanced pancreatic cancer
Eligibility
Age: 18 Years – 70 YearsHealthy volunteers accepted
Inclusion Criteria: 1. Ability to understand and sign a written informed consent documen; 2. At the date of signing ICF, 18 \~70 years old, male or female; 3. Histopathological confirmed advanced or metastatic pancreatic cancer patients who have failed to standard treatment or intolerance with standard treatment; 4. Positive mesothelin expression; 5. At least one measurable lesion at baseline per RECIST version 1.1; 6. The expected survival time is more than 12 weeks; 7. ECOG 0-1 points; 8. Adequate organ functions.
Conditions2
Advanced Pancreatic CancersCancer
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Actively Recruiting
PhasePhase 1
SponsorTianjin Medical University Cancer Institute and Hospital
Started2024-12-25
Est. completion2027-12-24
Eligibility
Age18 Years – 70 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →
NCT06760364