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Development of a Radiomics Model With MR to Predict the Occurence of a Infiltration of Muscoskeletal Tumor

RECRUITINGSponsored by IRCCS Azienda Ospedaliero-Universitaria di Bologna
Actively Recruiting
SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna
Started2025-03
Est. completion2028-09
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

The goal of this observational study is to evaluate the feasibility and clinical utility of radiomics to diagnose peri-lesion tumour infiltration of tumours in participants with a suspect of Bone Cancer Tumor or Soft Tissue Sarcoma (STS). The main questions it aims to answer are: * is radiomics able to identify the ratio of participants truly diagnosed as positive to all those who had positive test results? * is radiomics able to identify the likelihood that a participant who has a negative test result indeed does not have the disease? Participants eligible for this study will get a MRI as part of their regular medical care. The only difference is that their data will be recorded and anonymously analyzed.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Age over 18
* suspect of soft tissue sarcoma with a indication for surgical treatment
* suspect of bone cancer tumor with a indication for surgical treatment
* To give informed consent

Exclusion Criteria:

* simultaneous cancer or history of cancer in the last 5 years
* acute or chronic serious conditions that could
* contraindication to conduct a Contrast-enhanced magnetic resonance imaging (MRI) such as:

  * renal failure without dialysis
  * history of allergy to a paramagnetic contrast agent
  * claustrophobia
  * symptomatic epilepsy or history of epilepsy
  * cardiac pacemaker
  * infusion pump, prosthesis or any implant not compatible with MRI
  * pregnancy

Conditions3

Bone Cancer TumorCancerSoft Tissue Sarcoma (STS)

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