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Development of Organoids From Primary Colorectal Tumors and Synchronous Liver Metastases

RECRUITINGSponsored by Regina Elena Cancer Institute
Actively Recruiting
SponsorRegina Elena Cancer Institute
Started2024-05-25
Est. completion2028-01-25
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

Pilot feasibility study for the development of organoids from primary colorectal tumors and synchronous liver metastases, to prepare organoids from primary colorectal tumors and synchronous liver metastases. The organoids will allow us to study the function of genes targeted by the activity of the NF-Y/p53 complex.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Patients \> 18 years
* Histological and cytological diagnosis of colorectal cancer neoplasia that has developed a liver metastasis
* Patients who are candidates for surgery for colorectal cancer with liver metastasis
* Signing of the relevant informed consent form.

Exclusion Criteria:

* All exclusion criteria adopted in surgical protocols will be applied to the study

Conditions4

CancerColo-rectal CancerLiver CancerLiver Disease

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